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  • The Food and Drug Administration, FDA, has approved the drug Vivitrol for that treatment of opioid dependence according to a news release by them on 10-12-2010.

    Using two separate drugs to shed weight can be very effective you can find combinations in front of the FDA now awaiting approval. When dealing with weight reduction and the individuals who go through it you should err on the side of caution and allow FDA do its job and demand some research be done so that the public is aware of the side effects and perils associated with the medications before we bring them. Keep in mind that drug companies will be in business to make money and that they would say everything to keep people on the medications.

    Researchers found out that participants using this drug for the year, lost weight within one month and have kept the extra weight off through the 56 weeks with the study. Contrave can be a combination of the drugs naltrexone and bupropion, which appears to reflect a new trend of weight-loss drugs which can be made up of several active ingredient, which can make them far better and safer.

    Combo-pilling will be the newest fad or also the newest into the future under scrutiny and therefore it is just more publicly known in recent months, comb-pilling for losing weight has been around since the eighties. The biggest reason that by using a combination of pills is now popular will be the fact that as of right now there are not any long term prescription weightloss pills that have been licensed by the FDA besides orlistat. The truly disturbing part is always that doctors are prescribing these combinations of medications and some of the combinations have been rejected or have yet to be approved by the FDA.

    Seizures certainly are a side effect with Contrave and must not be taken in people with seizure disorders. The drug could also raise blood pressure and heartrate, and mustn't be used in those with a history of cardiac event or stroke in the last six months. Blood pressure and pulse should also be measured before commencing the drug and throughout therapy with all the drug.

    The FDA also warned that Contrave can raise blood pressure level and heartrate and must 't be used in patients with uncontrolled high blood pressure, as well as by you are not heart-related and cerebrovascular (blood vessel dysfunction impacting your brain) disease. Patients having a history of heart attack or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, considering that the compound includes bupropion, Contrave comes having a boxed warning to alert medical researchers and patients on the increased risk of suicidal thoughts and behaviors connected with antidepressant drugs. The warning also notes that serious neuropsychiatric events happen to be reported in patients taking bupropion for stopping smoking.

    From a psychiatric point of view, evidence implies that the ordinary neural mechanism for goal-directed behavior has become hijacked by the addiction, and malfunctions in such a way that its ordinary functions are exaggerated and fixated on its object. An object generates a stimulus as well as the person engages in a "goal-directed behavioral response" that produces a "natural high"(Bostwick & Bucci, 2008).

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